A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
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چکیده
منابع مشابه
Hydroxyl radical activation of a Ca(2+)-sensitive nonselective cation channel involved in epithelial cell necrosis.
In a previous work the involvement of a fenamate-sensitive Ca(2+)-activated nonselective cation channel (NSCC) in free radical-induced rat liver cell necrosis was demonstrated (5). Therefore, we studied the effect of radical oxygen species and oxidizing agents on the gating behavior of a NSCC in a liver-derived epithelial cell line (HTC). Single-channel currents were recorded in HTC cells by th...
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Simon, Felipe, Diego Varela, Ana Luisa Eguiguren, Laı́n F. Dı́az, Francisco Sala, and Andrés Stutzin. Hydroxyl radical activation of a Ca -sensitive nonselective cation channel involved in epithelial cell necrosis. Am J Physiol Cell Physiol 287: C963–C970, 2004. First published May 26, 2004; 10.1152/ajpcell.00041.2004.—In a previous work the involvement of a fenamate-sensitive Ca activated nonsel...
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The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in the fetal lung, but during lung development it gradually disappears in cells of future alveolar spaces. Recent studies have implicated the CFTR in fluid transport by the adult alveolar epithelium, but its presence has not been demonstrated directly. This study re-evaluated CFTR expression and activity in the adult pu...
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In pepsinogen-secreting cells of bullfrog (Rana catesbeiana), recent evidence suggests that Ca(2+) release from internal stores followed by Ca(2+) influx across the plasma membrane elicits pepsinogen secretion. Such a Ca(2+) influx could be carried by a background current, potentiated by bombesin, that was found in these cells using the whole cell patch-clamp technique. The permeability ratio o...
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SEIICHIRO KIMURA,1 HIROSHI MIENO,2 KENJI TAMAKI,3 MASAKI INOUE,4 AND KAZUAKI CHAYAMA5 1Saiseikai Kure Hospital, Kure City, Hiroshima 737-0821; 2Hiroshima General Hospital of the West Railroad Company, Hiroshima City, Hiroshima 732-0057; 3Chugoku Rosai Hospital, Kure City, Hiroshima 737-0193; and 4Department of Geriatric Medicine and First 5Department of Internal Medicine, Institute of Health Sc...
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ژورنال
عنوان ژورنال: Canadian Respiratory Journal
سال: 1994
ISSN: 1198-2241
DOI: 10.1155/1994/357537